134339-75-6Relevant articles and documents
Ruthenium-Catalyzed Chlorine Atom Transfer Cyclizations of N-Allylic α-Chloro-α-thioacetamides. Synthesis of (-)-Trachelanthamidine and Formal Total Synthesis of (+/-)-Haemanthidine and (+/-)-Pretazettine
Ishibashi, Hiroyuki,Uemura, Nahoko,Nakatani, Hiroshi,Okazaki, Mika,Sato, Tatsunori,et al.
, p. 2360 - 2368 (2007/10/02)
A new method for the synthesis of five-membered lactams by ruthenium-catalyzed chlorine atom transfer cyclizations of N-allylic α-chloro-α-thioacetamides and the application of the method to the synthesis of the title alkaloids are described.A benzene sol
Radical cyclizations of N-vinylic α-chloroacetamides. 5-Endo-trig and 4-exo-trig cyclizations
Ishibashi,Nakamura,Sato,Takeuchi,Ikeda
, p. 1725 - 1728 (2007/10/02)
Bu3SnH mediated radical cyclizations of N-vinylic α-chloroacetamides proceeded in a ''disfavored'' 5-endo-trig manner to give five-membered lactams. Some exceptions where the 4-exo cyclization predominates are also described.