134387-60-3

Basic information

• Product Name: cis-2-methoxy-6-phenyl-6-trifluoromethyltetrahydropyran-4-one
• CAS NO: 134387-60-3
• Molecular Weight: 274.24
• Mol File: 134387-60-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: cis-2-methoxy-6-phenyl-6-trifluoromethyltetrahydropyran-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: cis-2-methoxy-6-phenyl-6-trifluoromethyltetrahydropyran-4-one(134387-60-3)
• EPA Substance Registry System: cis-2-methoxy-6-phenyl-6-trifluoromethyltetrahydropyran-4-one(134387-60-3)

Safety Data

• Hazardous Substances Data: 134387-60-3(Hazardous Substances Data)

Upstream product

• 54125-02-9 danishefsky's diene 
• 434-45-7 2,2,2-Trifluoroacetophenone 

Relevant articles and documents

CYCLOADDITION OF 1-METHOXY-3-TRIMETHYLSILYLOXYBUTADIENE WITH HALOGENATED CARBONYL COMPOUNDS

Cycloadditions of 1-methoxy-3-trimethylsilyloxy-1,3-butadiene (1) with halogenated carbonyl compounds (2) yielded corresponding substituted tetrahydro- and/or dihydropyran-4-ones (3 and/or 4).Lewis acids were found to be effective as catalysts.Reactions with less reactive carbonyl compounds (2c,d) afforded p-hydroxyacetophenone (5) produced by cyclodimerization of 1.Stereochemistry of the adducts was deduced by 1H nmr spectroscopy.