1344109-47-2

Basic information

• Product Name: 2-bromo-4-(pyrrol-1-yl)benzyl alcohol
• Synonyms: 2-bromo-4-(pyrrol-1-yl)benzyl alcohol
• CAS NO: 1344109-47-2
• Molecular Weight: 252.11
• Mol File: 1344109-47-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-bromo-4-(pyrrol-1-yl)benzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-4-(pyrrol-1-yl)benzyl alcohol(1344109-47-2)
• EPA Substance Registry System: 2-bromo-4-(pyrrol-1-yl)benzyl alcohol(1344109-47-2)

Safety Data

• Hazardous Substances Data: 1344109-47-2(Hazardous Substances Data)

Upstream product

• 856794-72-4 2-bromo-4-nitrobenzoyl chloride 
• 98545-64-3 methyl-2-bromo-4-aminobenzoate 
• 100959-22-6 methyl 2-bromo-4-nitrobenzoate 
• 16426-64-5 2-bromo-4-nitrobenzoic acid 
• 7745-93-9 2-bromo-4-nitrotoluene 
• 1344109-43-8 2-bromo-4-(pyrrol-1-yl)benzoic acid methyl ester 

Downstream Products

• 1344109-66-5 phenyl(1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)pyrrol-2-yl)methanone 
• 1344109-55-2 phenyl(1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)pyrrol-3-yl)methanone 
• 1344109-58-5 4-fluorophenyl(1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)pyrrol-3-yl)methanone 
• 1344109-67-6 4-fluorophenyl(1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)pyrrol-2-yl)methanone 
• 1344109-70-1 2-chlorophenyl(1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)pyrrol-2-yl)methanone 
• 1344109-59-6 C₁₈H₁₃BClNO₃ 
• 1615684-90-6 6-(2-(4-chlorophenylsulfanyl)pyrrol-1-yl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole 
• 1615685-25-0 cyclohexyl(1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)pyrrol-3-yl)methanone 
• 1615685-23-8 2-phenylethyl(1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)pyrrol-3-yl)methanone 
• 1615685-22-7 benzyl(1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)pyrrol-3-yl)methanone 
• 1615685-13-6 3,4,5-trimethoxyphenyl(1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)pyrrol-3-yl)methanone 
• 1615685-12-5 2-methoxyphenyl(1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)pyrrol-3-yl)methanone 
• 1615685-10-3 4-ethylphenyl(1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)pyrrol-3-yl)methanone 
• 1615685-09-0 2-methylphenyl(1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)pyrrol-3-yl)methanone 

Relevant articles and documents

Novel pyrrolobenzoxaboroles: Design, synthesis, and biological evaluation against Trypanosoma brucei

Human African trypanosomiasis is a fatal parasitic infection caused by the protozoan Trypanosoma brucei. The development of novel antitrypanosomal agents is urgently needed. Here we report the synthesis and structure-activity relationship of a new class of benzoxaboroles as antitrypanosomal agents. These compounds showed antiparasitic IC50 values ranging from 4.02 to 0.03 μg/mL and satisfactory cytotoxicity profile. Three of the lead compounds were demonstrated to cure the parasitic infection in a murine acute infection model. The structure-activity relationship of the pyrrolobenzoxaboroles are also discussed.