134440-23-6

Basic information

• Product Name: benzimidazole 2'3'-dideoxyriboside
• Synonyms: benzimidazole 2'3'-dideoxyriboside
• CAS NO: 134440-23-6
• Molecular Weight: 218.255
• Mol File: 134440-23-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzimidazole 2'3'-dideoxyriboside(CAS DataBase Reference)
• NIST Chemistry Reference: benzimidazole 2'3'-dideoxyriboside(134440-23-6)
• EPA Substance Registry System: benzimidazole 2'3'-dideoxyriboside(134440-23-6)

Safety Data

• Hazardous Substances Data: 134440-23-6(Hazardous Substances Data)

Upstream product

• 51-17-2 benzoimidazole 
• 5983-09-5 2',3'-Dideoxyuridine 

Relevant articles and documents

Aeromonas hydrophila strains as biocatalysts for transglycosylation

Microbial transglycosylation is useful as a green alternative in the preparation of purine nucleosides and analogues, especially for those that display pharmacological activities. In a search for new transglycosylation biocatalysts, two Aeromonas hydrophila strains were selected. The substrate specificity of both micro-organisms was studied and, as a result, several nucleoside analogues have been prepared. Among them, ribavirin, a broad spectrum antiviral, and the well-known anti HIV didanosine, were prepared, in 77 and 62% yield using A. hydrophila CECT 4226 and A. hydrophila CECT 4221, respectively. In order to scale-up the processes, the reaction conditions, product purification and biocatalyst preparation were analyzed and optimized.