134453-12-6

Basic information

• Product Name: (2S,3S,5S)-benzyl 2-hexyl-3-<(tert-butyldimethylsilyl)oxy>-5-hydroxyhexadecanoate
• Synonyms: (2S,3S,5S)-benzyl 2-hexyl-3-<(tert-butyldimethylsilyl)oxy>-5-hydroxyhexadecanoate
• CAS NO: 134453-12-6
• Molecular Weight: 576.976
• Mol File: 134453-12-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S,5S)-benzyl 2-hexyl-3-<(tert-butyldimethylsilyl)oxy>-5-hydroxyhexadecanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,5S)-benzyl 2-hexyl-3-<(tert-butyldimethylsilyl)oxy>-5-hydroxyhexadecanoate(134453-12-6)
• EPA Substance Registry System: (2S,3S,5S)-benzyl 2-hexyl-3-<(tert-butyldimethylsilyl)oxy>-5-hydroxyhexadecanoate(134453-12-6)

Safety Data

• Hazardous Substances Data: 134453-12-6(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 68711-33-1 (3S,4S,6S)-3-Hexyl-3,4,5,6-tetrahydro-4-hydroxy-6-undecyl-2H-pyran-2-one 
• 100-39-0 benzyl bromide 
• 134360-67-1 (3S,4S,6S)-4-<(tert-butyldimethylsilyl)oxy>-3-hexyl-6-undecyltetrahydro-2H-pyran-2-one 

Downstream Products

• 134360-68-2 (2S,3S,5S)-benzyl 2-hexyl-3-<(tert-butyldimethylsilyl)oxy>-5-(benzyloxy)hexadecanoate 
• 134360-69-3 (2S,3S,5S)-benzyl 2-hexyl-3-hydroxy-5-(benzyloxy)hexadecanoate 
• 134453-14-8 (3S,4S,2'S)-3-hexyl-4-(2'-benzyloxytridec-1'-yl)oxetan-2-one 
• 134453-13-7 (2S,3S,5S)-5-(benzyloxy)-2-hexyl-3-hydroxyhexadecanoic acid 
• 104871-99-0 (3S,4S)-3-hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one 

Relevant articles and documents

Synthesis of Tetrahydrolipstatin

An asymmetric synthesis of tetrahydrolipstati (4) is described.Application of our previously described in situ cyclopentadiene alkylation-asymmetric hydroboration protocol provided the key chiral alcohol 9.In the course of this work, the presence of a free hydroxyl group was found to exert a strong directing effect on the regioselectivity of a Baeyer-Villiger reaction (16 --> 17).Subsequent transformations of lactone 17 produced tetrahydrolipstatin.