1345019-40-0Relevant articles and documents
Synthesis of Tetrahydroisoquinoline Alkaloids and Related Compounds through the Alkylation of Anodically Prepared α-Amino Nitriles
Benmekhbi, Lotfi,Louafi, Fadila,Roisnel, Thierry,Hurvois, Jean-Pierre
, p. 6721 - 6739 (2016)
α-Amino nitrile 2a was conveniently prepared in two individual steps from chiral hexafluorophosphate salt isoquinolinium (-)-8b including anodic cyanation as an efficient means to activate the sp3 C1-H bond of the THIQ nucleus. The lithiation o