1345514-83-1

Basic information

• Product Name: C₁₀H₁₀ClNO
• CAS NO: 1345514-83-1
• Molecular Weight: 195.648
• Mol File: 1345514-83-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₀H₁₀ClNO(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₁₀ClNO(1345514-83-1)
• EPA Substance Registry System: C₁₀H₁₀ClNO(1345514-83-1)

Safety Data

• Hazardous Substances Data: 1345514-83-1(Hazardous Substances Data)

Upstream product

• 22362-65-8 1-(5-chloro-2-hydroxy-4-methyl-phenyl)-propan-1-one 
• 1345514-61-5 C₁₀H₁₂ClNO 

Relevant articles and documents

A divergent and selective synthesis of isomeric benzoxazoles from a single N-Cl imine

A divergent and regioselective synthesis of either 3-substituted benzisoxazoles or 2-substituted benzoxazoles from readily accessible ortho-hydroxyaryl N-H ketimines is described. The reaction proceeds in two distinct pathways through a common N-Cl imine intermediate: (a) N-O bond formation to form benzisoxazole under anhydrous conditions and (b) NaOCl mediated Beckmann-type rearrangement to form benzoxazole, respectively. The reaction path also depends on the electronic nature of the aromatic ring, with the electron-rich aromatic rings favoring the rearrangement and the electron-deficient rings favoring the N-O bond formation. A Beckmann-type rearrangement mechanism via net [1,2]-aryl migration for the formation of 2-substituted benzoxazole is proposed.