1345697-33-7

Basic information

• Product Name: digitoxigenin 3-O-acetyl-2,6-dideoxy-4-O-(p-methoxybenzoyl)-α-D-ribo-hexopyranoside
• CAS NO: 1345697-33-7
• Molecular Weight: 680.836
• Mol File: 1345697-33-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: digitoxigenin 3-O-acetyl-2,6-dideoxy-4-O-(p-methoxybenzoyl)-α-D-ribo-hexopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: digitoxigenin 3-O-acetyl-2,6-dideoxy-4-O-(p-methoxybenzoyl)-α-D-ribo-hexopyranoside(1345697-33-7)
• EPA Substance Registry System: digitoxigenin 3-O-acetyl-2,6-dideoxy-4-O-(p-methoxybenzoyl)-α-D-ribo-hexopyranoside(1345697-33-7)

Safety Data

• Hazardous Substances Data: 1345697-33-7(Hazardous Substances Data)

Upstream product

• 57292-22-5 digitoxigen O-[2'',6''-dideoxy-β-D-ribo-hexopyranosyl]-(1->4)-O-[3'-O-acetyl-2',6'-dideoxy-β-D-ribo-hexopyranosyl]-(1->4)-(3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranoside 
• 1345697-20-2 methyl 2-deoxy-3-O-(p-methoxybenzoyl)-α-D-ribo-hexopyranoside 
• 1345697-24-6 methyl 3-O-acetyl-2,6-dideoxy-4-O-(p-methoxybenzoyl)-α-D-ribo-hexopyranoside 
• 1345697-27-9 3-O-acetyl-2,6-dideoxy-4-O-(p-methoxybenzoyl)-β-D-ribo-hexopyranosyl o-(cyclopropylethynyl)benzoate 
• 143-62-4 (+)-digitoxigenin 
• 1345697-19-9 methyl 4,6-O-benzylidene-2-deoxy-3-O-(p-methoxybenzoyl)-α-D-ribo-hexopyranoside 
• 71-63-6 digitoxin 

Relevant articles and documents

Assembly of digitoxin by gold(I)-catalyzed glycosidation of glycosyl o-alkynylbenzoates

Digitoxin, a clinically important cardiac trisaccharide, was assembled efficiently from digitoxigenin and 3,4-di-O-tert-butyldiphenylsilyl-d- digitoxosyl o-cyclopropylethynylbenzoate in 9 steps and 52% overall yield via alternate glycosylation and protecting group manipulation. The present synthesis showcases the advantage of the gold(I)-catalyzed glycosylation protocol in the synthesis of glycoconjugates containing acid-labile 2-deoxysugar linkages.