1345879-87-9 Usage
Description
(S)-1-chloro-3-[(4-chlorophenyl)methylene]aminopropan-2-ol, also known as levosalbutamol, is a chemical compound that belongs to the class of medications known as beta2-agonists. It is characterized by its ability to relax the muscles in the airways, facilitating easier breathing. Levosalbutamol is typically administered through inhalation and is recognized for its rapid onset of action, making it an effective treatment for acute symptoms of bronchospasm. Despite its generally well-tolerated nature, potential side effects may include tremors, palpitations, headaches, and an increased heart rate.
Uses
Used in Pharmaceutical Industry:
Levosalbutamol is used as a bronchodilator for the treatment of symptoms associated with asthma and chronic obstructive pulmonary disease (COPD). As a beta2-agonist, it works by relaxing the muscles in the airways, allowing for easier breathing and providing relief from acute symptoms of bronchospasm. Its rapid onset of action and effectiveness in managing respiratory conditions make it a valuable medication for improving the quality of life for individuals with breathing difficulties.
Check Digit Verification of cas no
The CAS Registry Mumber 1345879-87-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,4,5,8,7 and 9 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1345879-87:
(9*1)+(8*3)+(7*4)+(6*5)+(5*8)+(4*7)+(3*9)+(2*8)+(1*7)=209
209 % 10 = 9
So 1345879-87-9 is a valid CAS Registry Number.
1345879-87-9Relevant articles and documents
A Convenient Synthesis of Rivaroxaban from (S)-Epichlorohydrin
Halama, Ale?,Kruli?, Radim,Ryme?, Jan
, (2020/04/27)
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A convenient synthesis of the antibacterial agent linezolid
McCarthy, James R.
supporting information, p. 6846 - 6847 (2015/11/27)
Starting with 3,4-difluorobenzoic acid (8) and (S)-epichlorohydrin (13) a convergent synthesis of linezolid (1) was developed that is attractive for large scale preparation of the drug. The synthetic strategy involves a 1+3 cycloaddition reaction between the chiral epoxide 11 (prepared from 13) and isocyanate 3 (obtained from 8) that was generated in situ by a Curtius rearrangement. The resulting Schiff base precursor of linezolid (12) crystallized from the reaction mixture and was readily converted to linezolid by an acid-catalyzed hydrolysis followed by an acetylation.
PROCESSES FOR PREPARING RIVAROXABAN
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Page/Page column 18-19, (2013/10/22)
Processes and intermediates for preparing rivaroxaban, and analogs and derivatives thereof, and pharmaceutically acceptable salts of each of the foregoing, are described herein.
