1346133-08-1 Usage
General Description
LY-2795050, also known as BMS-262084, is a chemical compound that acts as a selective non-peptide antagonist for the melanin concentrating hormone receptor-1 (MCHR1). It has been studied for its potential applications in the treatment of obesity and related metabolic disorders. LY-2795050 has shown promising results in preclinical studies, demonstrating its ability to regulate food intake and weight gain in animal models. By blocking the MCHR1 receptor, LY-2795050 may offer a novel approach to controlling appetite and reducing excess body weight. Further research is necessary to determine the safety and efficacy of this compound for clinical use in humans.
Check Digit Verification of cas no
The CAS Registry Mumber 1346133-08-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,4,6,1,3 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1346133-08:
(9*1)+(8*3)+(7*4)+(6*6)+(5*1)+(4*3)+(3*3)+(2*0)+(1*8)=131
131 % 10 = 1
So 1346133-08-1 is a valid CAS Registry Number.
1346133-08-1Relevant articles and documents
Radiosynthesis of [11C]LY2795050 for Preclinical and Clinical PET Imaging Using Cu(II)-Mediated Cyanation
Yang, Lingyun,Brooks, Allen F.,Makaravage, Katarina J.,Zhang, Huibin,Sanford, Melanie S.,Scott, Peter J. H.,Shao, Xia
, p. 1274 - 1279 (2018)
Copper-mediated 11C-cyanation reactions have enabled the synthesis of PET radiotracers from a range of readily available precursors and avoid the need to use more toxic Pd catalysts. In this work we adapt our recently developed 11C-c
