1346756-52-2

Basic information

• Product Name: N-Ac-D-phenylalanine p-toluene thiol ester
• CAS NO: 1346756-52-2
• Molecular Weight: 313.42
• Mol File: 1346756-52-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-Ac-D-phenylalanine p-toluene thiol ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-Ac-D-phenylalanine p-toluene thiol ester(1346756-52-2)
• EPA Substance Registry System: N-Ac-D-phenylalanine p-toluene thiol ester(1346756-52-2)

Safety Data

• Hazardous Substances Data: 1346756-52-2(Hazardous Substances Data)

Upstream product

• 2901-75-9 (R,S)-N-acetyl phenylalanine 
• 106-45-6 para-thiocresol 
• 10172-89-1 (R)-N-acetylphenylalanin 

Relevant articles and documents

HMDO-promoted peptide and protein synthesis in ionic liquids

Hexamethyldisiloxane (HMDO) has been developed to efficiently promote the metal-free direct coupling of an amino function of one cysteine-free peptide or protein and a C-terminal thioester of the second peptide in ionic liquids. The amide-coupling reaction proceeds smoothly under mild conditions to afford the corresponding products in good to excellent yields (63-94%). Peptide couplings were also achieved using in-situ-generated thioesters by the thioesterification of oxo esters.