1346855-14-8

Basic information

• Product Name: 1-(2-(dimethylamino)-5-methoxyphenyl)naphthalene-2-ol
• Synonyms: 1-(2-(dimethylamino)-5-methoxyphenyl)naphthalene-2-ol
• CAS NO: 1346855-14-8
• Molecular Weight: 293.365
• Mol File: 1346855-14-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(2-(dimethylamino)-5-methoxyphenyl)naphthalene-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-(dimethylamino)-5-methoxyphenyl)naphthalene-2-ol(1346855-14-8)
• EPA Substance Registry System: 1-(2-(dimethylamino)-5-methoxyphenyl)naphthalene-2-ol(1346855-14-8)

Safety Data

• Hazardous Substances Data: 1346855-14-8(Hazardous Substances Data)

Upstream product

• 701-56-4 4-methoxy-N,N-dimethylanilne 
• 135-19-3 β-naphthol 

Relevant articles and documents

Aerobic Catalyzed Oxidative Cross-Coupling of N, N-Disubstituted Anilines and Aminonaphthalenes with Phenols and Naphthols

The cross-coupling of N,N-dialkyl aniline and aminonaphthalenes with phenols and naphthols using a Cr-salen catalyst under aerobic conditions was developed. Notably, air serves as an effective oxidant affording products in high selectivity. Initial mechanistic studies suggest an outer-sphere oxidation of the aniline/aminonaphthalene partner, followed by nucleophilic attack of the phenol/naphthol. Single products were observed in most cases, whereas mixtures of C-C and C-O coupled products arose from reactions involving aminonapthalene and sterically unencumbered phenols.

Cerium-containing MCM-41 catalyst for selective oxidative arene cross-dehydrogenative coupling reactions

Cerium (IV)-mediated intermolecular direct biaryl coupling of aromatic tertiary amines and naphthol via dual CH bond activation has been reported. The new CC bond is formed regioselectively ortho to the amino and hydroxyl substituents under oxidative conditions to give substituted bifunctional amino naphthols. We report here the use of Ce-MCM-41 catalyst for the synthesis of these unsymmetrical biaryls via oxidative cross coupling under mild conditions. The catalyst was recovered by simple filtration and reused for several cycles with consistent activity.