1348211-74-4Relevant articles and documents
Exploring Epidermal Growth Factor Receptor (EGFR) inhibitor features: The role of fused dioxygenated rings on the quinazoline scaffold
Chilin, Adriana,Conconi, Maria Teresa,Marzaro, Giovanni,Guiotto, Adriano,Urbani, Luca,Tonus, Francesca,Parnigotto, Pierpaolo
supporting information; experimental part, p. 1862 - 1866 (2010/08/06)
A number of dioxolane, dioxane, and dioxepine quinazoline derivatives have been synthetized, and evaluated as EGFR inhibitors. Their cytotoxic activity has been tested against two cell, lines overexpressing and not expressing EGFR. Most derivatives were a