13484-04-3

Basic information

• Product Name: 3-(4-BROMOPHENYL)ISOXAZOLE
• Synonyms: 3-(4-BROMOPHENYL)ISOXAZOLE;3-(4-Bromophenyl)isoxazol...
• CAS NO: 13484-04-3
• Molecular Formula: C₉H₆BrNO
• Molecular Weight: 224.05
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Isoxazoles;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 13484-04-3.mol
• Article Data: 13

Chemical Properties

• Melting Point: 99-104 °C
• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-(4-BROMOPHENYL)ISOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-BROMOPHENYL)ISOXAZOLE(13484-04-3)
• EPA Substance Registry System: 3-(4-BROMOPHENYL)ISOXAZOLE(13484-04-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 13484-04-3(Hazardous Substances Data)

Usage

General Description

3-(4-Bromophenyl)isoxazole, also known as 4-Bromo-3-phenylisoxazole, is a chemical compound with the molecular formula C9H6BrNO. It is a heterocyclic compound consisting of a five-membered ring containing oxygen and nitrogen atoms. 3-(4-BROMOPHENYL)ISOXAZOLE is used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active molecules and pharmaceutical compounds. Its applications include as a scaffold for potential drug candidates and as a ligand in coordination chemistry. 3-(4-Bromophenyl)isoxazole is a versatile intermediate that has potential for use in various chemical and pharmaceutical industries.

Upstream product

• 850379-97-4 3-(4-bromophenyl)-5-(trimethylsilyl)isoxazole 
• 37614-58-7 3-(4-bromophenyl)prop-2-yn-1-ol 
• 1122-91-4 4-bromo-benzaldehyde 
• 1606168-00-6 C₁₄H₁₁BrNO⁽¹⁺⁾*Br^(1-) 
• 49678-04-8 4-bromocinnamaldeyde 
• 73387-60-7 (2E)-1-(4-bromophenyl)-3-(dimethylamino)prop-2-en-1-one 
• 14063-78-6 (Z)-3-(4-bromophenyl)-3-chloroacrylaldehyde 
• 42811-75-6 p-bromobenzonitrile N-oxide 
• 29203-58-5 4-bromo-N-hydroxybenzenecarboximidoyl chloride 
• 25062-46-8 4-bromobenzaldehyde oxime 
• 105515-33-1 (2E)-3-(4-bromophenyl)prop-2-en-1-ol 
• 20451-53-0 Phenyl vinyl sulfoxide 
• 521075-50-3 (Z)-3-azido-3-(4-bromophenyl)prop-2-en-1-ol 
• 76439-10-6 C₁₈H₂₄BrN₃O₃ 

Downstream Products

• 1358779-00-6 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]isoxazole 
• 1312474-14-8 (2R)-N-hydroxy-4-[4-(4-isoxazol-3-ylphenyl)-2-oxopyridin-1(2H)-yl]-2-methyl-2-(methylsulfonyl)butanamide 
• 1358779-01-7 (2R)-4-[4-(4-isoxazol-3-ylphenyl)-2-oxopyridin-1(2H)-yl]-2-methyl-2-(methylsulfonyl)-N-(tetrahydro-2H-pyran-2-yloxy)butanamide 

Relevant articles and documents

Preparation method of isoxazole derivative

The invention relates to a preparation method of an isoxazole derivative, which comprises the following steps of mixing an propargyl alcohol derivative, a halogen source, an acid and a solvent, and heating to react; adding the hydroxylamine into the react

Efficient and regioselective one-pot synthesis of 3-substituted and 3,5-disubstituted isoxazoles

(Figure Presented) A series of 3-substituted and 3,5-disubstituted isoxazoles have been efficiently synthesized in moderate to excellent yields by the reaction of N-hydroxyl-4-toluenesulfonamide with α,β-unsaturated aldehydes/ketones. This novel strategy is associated with readily available starting materials, mild conditions, high regioselectivity, and wide scope.

Reaction of β-dimethylaminovinyl ketones with hydroxylamine: A simple and useful method for synthesis of 3- and 5-substituted isoxazoles

(Chemical Equation Presented) The regioselective synthesis of 3- and 5-substituted-isoxazoles from the reaction of β-dimethylaminovinyl ketones [R-C(O)CH=CH-NMe2, where R = Ph, MeO-4-C6H4, F-4-C6H4, C