134999-89-6

Basic information

• Product Name: 4-[2-(4-tert-butylphenyl)ethoxy]pyrido[2,3-d]pyrimidine
• Synonyms: 4-[2-(4-tert-Butylphenyl)ethoxy]pyrido[2,3-d]pyrimidine; pyrido[2,3-d]pyrimidine, 4-[2-[4-(1,1-dimethylethyl)phenyl]ethoxy]-
• CAS NO: 134999-89-6
• Molecular Formula: C₁₉H₂₁N₃O
• Molecular Weight: 307.3895
• Mol File: 134999-89-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 468.6°C at 760 mmHg
• Flash Point: 167.5°C
• Density: 1.133g/cm³
• Vapor Pressure: 1.66E-08mmHg at 25°C
• Refractive Index: 1.598
• CAS DataBase Reference: 4-[2-(4-tert-butylphenyl)ethoxy]pyrido[2,3-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(4-tert-butylphenyl)ethoxy]pyrido[2,3-d]pyrimidine(134999-89-6)
• EPA Substance Registry System: 4-[2-(4-tert-butylphenyl)ethoxy]pyrido[2,3-d]pyrimidine(134999-89-6)

Safety Data

• Hazardous Substances Data: 134999-89-6(Hazardous Substances Data)

Usage

Commonly Known As

E6201

Type

Synthetic organic compound

Use

Pharmaceutical applications

Mechanism of Action

Potent and selective inhibitor of MEK1/2

Role

Inhibits the MAPK/ERK signaling pathway involved in cell proliferation and survival

Potential Applications

Treatment of cancers like melanoma and non-small cell lung cancer

Effect

Inhibits abnormal cell growth and division

Combination

Can be used in combination therapies with other cancer drugs

Research Status

Still undergoing research and development

Potential

Promising as a targeted therapy for certain types of cancer

Importance

Significant compound in the field of oncology.