1350431-00-3Relevant articles and documents
Nickel-catalyzed heck-type reactions of benzyl chlorides and simple olefins
Matsubara, Ryosuke,Gutierrez, Alicia C.,Jamison, Timothy F.
supporting information; experimental part, p. 19020 - 19023 (2011/12/21)
Nickel-catalyzed intermolecular benzylation and heterobenzylation of unactivated alkenes to provide functionalized allylbenzene derivatives are described. A wide range of both the benzyl chloride and alkene coupling partners are tolerated. In contrast to analogous palladium-catalyzed variants of this process, all reactions described herein employ electronically unbiased aliphatic olefins (including ethylene), proceed at room temperature, and provide 1,1-disubstituted olefins over the more commonly observed 1,2-disubstituted olefins with very high selectivity.
