1350644-53-9

Basic information

• Product Name: 1,3-dihydro-1-ferrocenylmethyl-5-phenyl-2H-1,4-benzodiazepin-2-one
• CAS NO: 1350644-53-9
• Molecular Weight: 434.32
• Mol File: 1350644-53-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-dihydro-1-ferrocenylmethyl-5-phenyl-2H-1,4-benzodiazepin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dihydro-1-ferrocenylmethyl-5-phenyl-2H-1,4-benzodiazepin-2-one(1350644-53-9)
• EPA Substance Registry System: 1,3-dihydro-1-ferrocenylmethyl-5-phenyl-2H-1,4-benzodiazepin-2-one(1350644-53-9)

Safety Data

• Hazardous Substances Data: 1350644-53-9(Hazardous Substances Data)

Upstream product

• 2898-08-0 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one 

Relevant articles and documents

One-pot microwave-assisted synthesis and antimalarial activity of ferrocenyl benzodiazepines

An efficient synthesis of 1,4-benzodiazepin-2-ones is described by condensation between 2-aminobenzophenone and Boc-protected amino acids via microwave-assisted irradiation. This produces higher yields in shorter reaction times than with traditional methods. The antiplasmodial activity of the corresponding ferrocenyl benzodiazepines was evaluated in vitro against Plasmodium falciparum F32 (chloroquine-sensitive) and FCB1 and K1 (chloroquine-resistant) strains and gabonese clinical isolates.