13507-15-8 Usage
Description
Acetamide hydrochloride, with the molecular formula C2H5NO.HCl, is a white crystalline solid that is soluble in water and ethanol. It has a melting point of 114-116°C and is used in various applications, including pharmaceuticals, organic synthesis, and the production of aniline, dyes, and pesticides. It has also been studied for its potential antineoplastic activity, making it a subject of interest in cancer research. However, it is important to handle and use this chemical with caution due to its potential to irritate the skin, eyes, and respiratory system.
Uses
Used in Pharmaceutical Industry:
Acetamide hydrochloride is used as a pharmaceutical intermediate for the synthesis of various drugs. It plays a crucial role in the development of new medications and contributes to the advancement of pharmaceutical research.
Used in Organic Synthesis:
Acetamide hydrochloride serves as a reagent in organic synthesis, enabling the production of various organic compounds. Its versatility as a reagent makes it valuable in the field of organic chemistry.
Used in Chemical Production:
Acetamide hydrochloride is utilized in the production of aniline, dyes, and pesticides. Its presence in these industries highlights its importance in the synthesis of a wide range of chemical products.
Used in Cancer Research:
Acetamide hydrochloride has been studied for its potential antineoplastic activity, making it a subject of interest in cancer research. Its potential to inhibit the growth of cancer cells has attracted the attention of researchers, who are exploring its therapeutic applications in oncology.
Check Digit Verification of cas no
The CAS Registry Mumber 13507-15-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,5,0 and 7 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 13507-15:
(7*1)+(6*3)+(5*5)+(4*0)+(3*7)+(2*1)+(1*5)=78
78 % 10 = 8
So 13507-15-8 is a valid CAS Registry Number.
13507-15-8Relevant articles and documents
Efficient transformation of nitrile into amide under mild condition
Basu, Manas K.,Luo, Fen-Tair
, p. 3005 - 3006 (1998)
Transformation of various kinds of nitriles into the corresponding amides or amide salts was performed in good yields by the addition of two equiv of chlorotrimethylsilane and two equiv of water at 0°C to 25°C.
Amide substituted imidazopyridines
-
, (2008/06/13)
Imidazopyridine compounds that contain amide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
Certain alpha-substituted arylsulfonamido acetohydroxamic acids
-
, (2008/06/13)
Particularly the invention relates to the compounds of formula I STR1 wherein Ar represents carbocyclic aryl, heterocyclic aryl or biaryl; R1 represents lower alkyl, cycloalkyl, aryl-lower alkyl, lower alkoxy-lower alkyl, aryl, cycloalkyl-lower alkyl, halo-lower alkyl; R2 represents hydrogen or lower alkyl; R3 and R4 represent independently hydrogen, lower alkyl, lower alkoxy, halo, hydroxy, acyloxy, lower alkoxy-lower alkoxy, trifluoromethyl or cyano; or R3 and R4 together represent lower allylenedioxy; n represents an integer from 1 to 5; pharmaceutically acceptable prodrug derivatives; and pharmaceutically acceptable salts thereof; methods for preparation thereof; pharmaceutical compositions comprising said compounds; and a method of inhibiting TNF-alpha activity and matrix-degrading metalloproteinases in mammals using such compounds.
