1350730-58-3

Basic information

• Product Name: C₂₇H₂₄N₃O₅⁽¹⁺⁾*Cl^(1-)
• Synonyms: C₂₇H₂₄N₃O₅⁽¹⁺⁾*Cl^(1-)
• CAS NO: 1350730-58-3
• Molecular Weight: 505.958
• Mol File: 1350730-58-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₇H₂₄N₃O₅⁽¹⁺⁾*Cl^(1-)(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₂₄N₃O₅⁽¹⁺⁾*Cl^(1-)(1350730-58-3)
• EPA Substance Registry System: C₂₇H₂₄N₃O₅⁽¹⁺⁾*Cl^(1-)(1350730-58-3)

Safety Data

• Hazardous Substances Data: 1350730-58-3(Hazardous Substances Data)

Upstream product

• 24954-67-4 2-(p-nitrophenyl)ethylamine 
• 633-65-8 berberine chloride 

Relevant articles and documents

Synthesis, biological evaluation of 9-N-substituted berberine derivatives as multi-functional agents of antioxidant, inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation

A series of 9-N-substituted berberine derivatives were synthesized and biologically evaluated as antioxidant and inhibitors of acetylcholinesterase (AChE), butyrylcholinesterase and amyloid-β aggregation. Most of these compounds exhibited very good antioxidant activities, inhibitive activities of AChE and amyloid-β aggregation. Among them, compound 8d, (o-methylphenethyl)amino linked at the 9-position of berberine, was found to be a good antioxidant (with 4.05 μM of Trolox equivalents), potent inhibitor of AChE (an IC50 value of 0.027 μM), and high active inhibitor of amyloid-β aggregation (an IC50 value of 2.73 μM).