1350897-04-9

Basic information

• Product Name: (S)-2-(2,5-dioxo-1-phenylpyrrolidin-3-yl)-2-ethylbutanal
• Synonyms: (S)-2-(2,5-dioxo-1-phenylpyrrolidin-3-yl)-2-ethylbutanal
• CAS NO: 1350897-04-9
• Molecular Weight: 273.332
• Mol File: 1350897-04-9.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (S)-2-(2,5-dioxo-1-phenylpyrrolidin-3-yl)-2-ethylbutanal(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(2,5-dioxo-1-phenylpyrrolidin-3-yl)-2-ethylbutanal(1350897-04-9)
• EPA Substance Registry System: (S)-2-(2,5-dioxo-1-phenylpyrrolidin-3-yl)-2-ethylbutanal(1350897-04-9)

Safety Data

• Hazardous Substances Data: 1350897-04-9(Hazardous Substances Data)

Upstream product

• 97-96-1 2-Ethylbutyraldehyde 
• 941-69-5 N-phenyl-maleimide 

Downstream Products

• 1431769-16-2 (S)-2-(4,4-diethyl-2-oxotetrahydrofuran-3-yl)-N-phenylacetamide 

Relevant articles and documents

Asymmetric Michael addition organocatalyzed by α,β-dipeptides under solvent-free reaction conditions

The application of six novel α,β-dipeptides as chiral organocatalysts in the asymmetric Michael addition reaction between enolizable aldehydes and N-arylmaleimides or nitroolefins is described. With N-arylmaleimides as substrates, the best results were achieved with dipeptide 2 as a catalyst in the presence of aq. NaOH. Whereas dipeptides 4 and 6 in conjunction with 4-dimethylaminopyridine (DMAP) and thiourea as a hydrogen bond donor proved to be highly efficient organocatalytic systems in the enantioselective reaction between isobutyraldehyde and various nitroolefins.

Stereoselective conjugate addition of carbonyl compounds to maleimides using a diaminomethyleneindenedione organocatalyst

A diaminomethyleneindenedione motif can serve as an excellent double hydrogen bonding donor. Bifunctional chiral primary amine 3 bearing a diaminomethyleneindenedione motif is an excellent organocatalyst to promote the asymmetric conjugate additions of va

Solvent-dependent enantioswitching in the Michael addition of α,α-disubstituted aldehydes to maleimides organocatalyzed by mono-N-Boc-protected cyclohexa-1,2-diamines

Enantiomerically pure mono-N-Boc-protected trans-cyclohexa-1,2-diamines are used as organocatalysts for the enantioselective conjugate addition of α,α-disubstituted aldehydes to maleimides. Using a single enantiomer of the organocatalyst, both enantiomeri