1350899-04-5

Basic information

• Product Name: (E)-1-(4-hydroxy-3-methoxybenzylidene)-4-(4-fluorophenyl)semicarbazone
• CAS NO: 1350899-04-5
• Molecular Weight: 303.293
• Mol File: 1350899-04-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-(4-hydroxy-3-methoxybenzylidene)-4-(4-fluorophenyl)semicarbazone(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(4-hydroxy-3-methoxybenzylidene)-4-(4-fluorophenyl)semicarbazone(1350899-04-5)
• EPA Substance Registry System: (E)-1-(4-hydroxy-3-methoxybenzylidene)-4-(4-fluorophenyl)semicarbazone(1350899-04-5)

Safety Data

• Hazardous Substances Data: 1350899-04-5(Hazardous Substances Data)

Upstream product

• 121-33-5 vanillin 
• 153885-60-0 N-(4-fluorophenyl)hydrazinecarboxamide 
• 371-40-4 4-fluoroaniline 
• 65141-04-0 phenyl N-(4-fluorophenyl)carbamate 

Relevant articles and documents

Synthesis and characterization of vanillin semicarbazones

Semicarbazones have a great interest because of their chemistry and biological activities for the treatment of various human ailments. A series of seven vanillin semicarbazones (3a-g) were synthesized by reflux of aryl semicarbazides with appropriate carbonyl compound in the presence of glacial acetic acid. The aryl semicarbazides (2a-g) were synthesized from aryl carbamates by reacting with hydrazine hydrate and ethanol on hydrazinolysis. The aryl carbamates (1a-g) were obtained by the reaction between phenyl chloro formate and aniline/substituted aniline in anhydrous ether in the presence of sodium hydroxide. The structure of the newly synthesized compounds was established by various analytical techniques such as IR, 1H NMR and MASS spectral studies.