1351706-37-0

Basic information

• Product Name: N-(2-iodo-4-chlorophenyl)-4-methylbenzenesulfonamide
• Synonyms: N-(2-iodo-4-chlorophenyl)-4-methylbenzenesulfonamide
• CAS NO: 1351706-37-0
• Molecular Weight: 407.659
• Mol File: 1351706-37-0.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: N-(2-iodo-4-chlorophenyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-iodo-4-chlorophenyl)-4-methylbenzenesulfonamide(1351706-37-0)
• EPA Substance Registry System: N-(2-iodo-4-chlorophenyl)-4-methylbenzenesulfonamide(1351706-37-0)

Safety Data

• Hazardous Substances Data: 1351706-37-0(Hazardous Substances Data)

Upstream product

• 63069-48-7 p-chloro-o-iodoaniline 
• 98-59-9 p-toluenesulfonyl chloride 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 1429887-45-5 5-chloro-2,3-dimethyl-1-[(4-methylphenyl)sulfonyl]-1H-indole 
• 1427548-48-8 C₃₃H₃₂ClN₅O₂S₂ 
• 1404202-65-8 2-tert-butyl-5-chloro-1-tosyl-1H-indole 
• 1404203-00-4 2-tert-butyl-5-chloro-7-tosyl-1H-indole 
• 1404202-85-2 1-(2-tert-butyl-5-chloro-7-tosyl-1H-indol-3-yl)propan-1-one 
• 1404202-83-0 1-(2-tert-butyl-5-chloro-7-tosyl-1H-indol-3-yl)ethanone 
• 1591916-40-3 C₁₆H₁₃ClINO₂S 

Relevant articles and documents

Nickel-Catalyzed trans-Carboamination across Internal Alkynes to Access Multifunctionalized Indoles

A Ni-catalyzed reaction was developed for the synthesis of multifunctionalized indoles. The reaction proceeded through oxidative cyclization of the Ni(0)/P^N complex with an enyne system, 2-alkynyl anilinoacrylate, to provide a nickelacycle intermediate. The trans-carboamination around the internal alkyne was achieved by syn/anti-rotation of the Ni-carbenoid intermediate formed by C-N bond cleavage of the nickelacycle, and 3-alkenylated indoles were formed by C-N bond-forming reductive elimination. Notably, the synthesized indoles could be successfully transformed to functionalized carbazoles.

Palladium-Catalyzed Allenamide Carbopalladation/Allylation with Active Methine Compounds

A palladium-catalyzed allenamide carbopalladation/allylation with active methine compounds has been developed. Various indoles and isoquinolinones bearing a quaternary carbon center were achieved with good efficiency, a broad substrate scope and good functional group tolerance. This reaction underwent cascade oxidative addition, carbopalladation, and allylic alkylation, and two new C-C bonds were formed in one pot.

Organocatalytic Asymmetric Annulation of ortho-Alkynylanilines: Synthesis of Axially Chiral Naphthyl-C2-indoles

A chiral Br?nsted base catalyzed asymmetric annulation of ortho-alkynylanilines has been developed to access axially chiral naphthyl-C2-indoles via vinylidene ortho-quinone methide (VQM) intermediates. This strategy provides a unique organocatalytic atrop