135247-43-7

Basic information

• Product Name: Butanoic acid, 2,4-dihydroxy-, methyl ester
• CAS NO: 135247-43-7
• Molecular Formula: C5H10O4
• Molecular Weight: 134.132
• Mol File: 135247-43-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 2,4-dihydroxy-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2,4-dihydroxy-, methyl ester(135247-43-7)
• EPA Substance Registry System: Butanoic acid, 2,4-dihydroxy-, methyl ester(135247-43-7)

Safety Data

• Hazardous Substances Data: 135247-43-7(Hazardous Substances Data)

Upstream product

• 38115-87-6 malic acid dimethyl ester 
• 67-56-1 methanol 
• 19444-84-9 3-hydroxyoxolan-2-one 

Downstream Products

• 20825-71-2 2(3H)-furanone 
• 19444-84-9 3-deoxy-L-glycero-tetronolactone 
• 307532-01-0 (R)-methyl 4-(tert-butyldimethylsilyloxy)-2-hydroxybutanoate 
• 307532-01-0 methyl (2S)-4-[(tert-butyldimethylsilyl)oxy]-2-hydroxybutanoate 
• 307532-01-0 methyl 4-[(tert-butyldimethylsilyl)oxy]-2-hydroxybutanoate 

Relevant articles and documents

Ru/SiO2 Catalyst for Highly Selective Hydrogenation of Dimethyl Malate to 1,2,4-Butanetriol at Low Temperatures in Aqueous Solvent

Catalytic selective hydrogenation of esterified malic acid to produce 1,2,4-butanetriol (1,2,4-BT) using H2 as the reducing reagent suffers from the low 1,2,4-BT selectivity. Here, Ru/SiO2 catalyst was employed for selective hydrogenation of dimethyl malate (DM) to produce 1,2,4-BT, which gave abnormal high DM conversion (100%) and 1,2,4-BT selectivity (92.4%) in aqueous solvent at 363?K, especially, the 1,2,4-BT yield even is higher than the optimal catalyst reported (Ru-Re, 79.8%). The reaction pathways for the DM hydrogenation on Ru/SiO2 were also proposed, suggesting that extremely high 1,2,4-BT selectivity require for the much high hydrogenation rates at low temperatures, where side-reaction transesterification rates are relatively low. The extremely high hydrogenation activity and 1,2,4-BT selectivity on Ru/SiO2 in aqueous solvent at low temperatures arise from that H2O may coordinate to Ru2+ and prevent the reduction of Ru2+ to Ru under high H2 pressure. Ru/SiO2 surface presents abundant Ru2+ in aqueous solvent, can activate H2 through heterolytic cleavage mode to form hydride, which can significantly increase hydrogenation rates of C = O groups at low temperatures. In addition, the activity and 1,2,4-BT selectivity on Ru/SiO2 catalyst only reduced by 2.3% and 2.6%, respectively over a period of 550?h. Graphical Abstract: [Figure not available: see fulltext.]