1352558-62-3

Basic information

• Product Name: 4,4-bis(2-phenylethyl)-1-triisopropylsilyl-1,4-dihydropyridine
• Synonyms: 4,4-bis(2-phenylethyl)-1-triisopropylsilyl-1,4-dihydropyridine
• CAS NO: 1352558-62-3
• Molecular Weight: 445.764
• Mol File: 1352558-62-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4,4-bis(2-phenylethyl)-1-triisopropylsilyl-1,4-dihydropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-bis(2-phenylethyl)-1-triisopropylsilyl-1,4-dihydropyridine(1352558-62-3)
• EPA Substance Registry System: 4,4-bis(2-phenylethyl)-1-triisopropylsilyl-1,4-dihydropyridine(1352558-62-3)

Safety Data

• Hazardous Substances Data: 1352558-62-3(Hazardous Substances Data)

Upstream product

• 2116-64-5 4-(2-phenylethyl)pyridine 
• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 
• 103-63-9 1-phenyl-2-bromoethane 
• 6928-73-0 bis(phenethyl)magnesium 

Downstream Products

• 1352558-67-8 4,4-bis(2-phenylethyl)piperidine-2,6-dicarbonitrile 
• 1352558-75-8 4,4-bis(2-phenylethyl)-1-triisopropylsilyl-1,2,3,4-tetrahydropyridine-2-carbonitrile 
• 1352558-72-5 4,4-bis(2-phenylethyl)-1-triisopropylsilylpiperidine-cis-2,6-dicarbonitrile 
• 1352558-78-1 1-acetyl-4,4-bis(2-phenylethyl)-1,2,3,4-tetrahydropyridine-2-carbonitrile 
• 1352558-81-6 4,4-bis(2-phenylethyl)piperidine-2-carbonitrile 
• 1352558-84-9 4,4-bis(2-phenylethyl)piperidine-2-carboxylic acid hydrochloride 
• 1352558-89-4 4,4-bis(2-phenylethyl)piperidine-cis-2,6-dicarboxylic acid hydrochloride 

Relevant articles and documents

Inter- and intramolecular [4+2]-cycloaddition reactions with 4,4-disubstituted N -silyl-1,4-dihydropyridines as precursors for N-protonated 2-azabutadiene intermediates

An efficient and straightforward method for the synthesis of polycyclic ring systems with a central 2-azabicyclo[2.2.2]octane unit is developed. The process is based on [4+2]-cycloaddition reactions that are performed with N-protonated 2-azabutadiene intermediates as heterodienes, generated from 4,4-disubstituted N-silyl 1,4-dihydropyridines. As dienophiles, cyclopentadiene for the intermolecular cycloaddition and an allyl moiety already attached to the 4,4-disubstituted 1,4-dihydropyridines for the intramolecular variant, are used.