1352662-99-7

Basic information

• Product Name: (S)-1-{2-[(di-tert-butylphosphino)methyl]pyrrolidin-1-yl}-2,2,2-triphenylethanone
• CAS NO: 1352662-99-7
• Molecular Weight: 499.676
• Mol File: 1352662-99-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-1-{2-[(di-tert-butylphosphino)methyl]pyrrolidin-1-yl}-2,2,2-triphenylethanone(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-{2-[(di-tert-butylphosphino)methyl]pyrrolidin-1-yl}-2,2,2-triphenylethanone(1352662-99-7)
• EPA Substance Registry System: (S)-1-{2-[(di-tert-butylphosphino)methyl]pyrrolidin-1-yl}-2,2,2-triphenylethanone(1352662-99-7)

Safety Data

• Hazardous Substances Data: 1352662-99-7(Hazardous Substances Data)

Upstream product

• 128542-75-6 (S)-2-(bromomethyl)-1-<(tert-butyloxy)carbonyl>pyrrolidine 
• 128363-76-8 di-tert-butylphosphine borane 

Relevant articles and documents

Chiral proline-based P,O and P,N ligands for iridium-catalyzed asymmetric hydrogenation

Two new classes of proline-based P,O and P,N ligands were prepared and applied in the iridium-catalyzed asymmetric hydrogenation of alkenes. Both types of ligands induced high enantioselectivities in the hydrogenation of trisubstituted C=C bonds. Iridium complexes derived from P,O ligands bearing sterically demanding amide or urea groups at the pyrrolidine N-atom proved to be especially efficient catalysts for the conjugate reduction of α,β-unsaturated esters and ketones, whereas analogous P,N ligands led to better results with dialkyl-phenyl-substituted alkenes and an allylic alcohol as substrates.