1352709-73-9

Basic information

• Product Name: (diphenylphosphoryl)(N,N-dimethylamino)chloromethane
• Synonyms: (diphenylphosphoryl)(N,N-dimethylamino)chloromethane
• CAS NO: 1352709-73-9
• Molecular Weight: 293.733
• Mol File: 1352709-73-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (diphenylphosphoryl)(N,N-dimethylamino)chloromethane(CAS DataBase Reference)
• NIST Chemistry Reference: (diphenylphosphoryl)(N,N-dimethylamino)chloromethane(1352709-73-9)
• EPA Substance Registry System: (diphenylphosphoryl)(N,N-dimethylamino)chloromethane(1352709-73-9)

Safety Data

• Hazardous Substances Data: 1352709-73-9(Hazardous Substances Data)

Upstream product

• 1079-66-9 chloro-diphenylphosphine 
• 68-12-2 N,N-dimethyl-formamide 
• 3724-43-4 Vilsmeier reagent 

Downstream Products

• 1131544-86-9 N,N-dimethyl-(diphenylphosphinomethylene)iminium iodide 
• 89175-77-9 2-(diphenylphosphoryl)butan-2-ol 
• 18975-51-4 diphenyl(N,N-diethylaminomethyl)phosphine oxide 
• 23650-05-7 (dimethylamino)(diphenylphosphinoyl)(diethoxyphosphinoyl)methane 
• 23587-60-2 N,N-dimethylaminobis(diphenylphosphoryl)methane 
• 15453-04-0 (1-Hydroxy-1-methylethyl)-diphenylphosphine oxide 
• 1373368-78-5 (dimethoxyphosphinoyl)(dimethylamino)(diphenylphosphinoyl)methane 
• 20570-20-1 (Diethoxymethyl)diphenylphosphine oxide 
• 71574-48-6 bis(p-dimethylaminophenyl)(diphenylphosphinoyl)methane 
• 25419-99-2 (dimethylamino)(diphenylphosphinoyl)methoxymethane 
• 38828-07-8 diphenyl(α-hydroxy)ethylphosphine oxide 
• 7067-73-4 N-phenyl(diphenylphosphinoyl)formamide 
• 100-44-7 benzyl chloride 
• 68-12-2 N,N-dimethyl-formamide 

Relevant articles and documents

Synthesis of polyfunctional methylphosphine oxides

-

Synthesis of polyfunctionalized methylphosphine oxides

N,N-Dialkylamino(diphenylphosphoryl)chloromethanes, a new type of organophosphorus compounds, were synthesized. On dissolving in polar and low polar solvents, N,N-dialkylamino(diphenylphosphoryl)chloromethanes dissociate spontaneously with the P - C bond cleavage to form the diphenylphosphinite anion Ph2PO-. This was confirmed by the reaction of N,N-dimethylamino(diphenylphosphoryl)chloromethane with electrophilic substrates to form the corresponding addition or substitution products of Ph 2PO-. The capability of spontaneous generating the diphenylphosphinite anion considers accessible N,N- dimethylamino(diphenylphosphoryl)chloromethane as a synthetic equivalent of the diphenylphosphinite anion.

A scheme of the stepwise reaction of diphenylchlorophosphine with N,N-dialkylformamides in the presence of NaI

On an example of DMF was proposed and experimentally verified stepwise reaction scheme of the reaction of diphenylchlorophosphine with N,N-dialkylformamides. The first stage is autocatalytic reaction of the synthesis of (diphenylphosphoryl)(N,N-dialkylami