1353244-45-7Relevant articles and documents
Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: Synthesis of novel α- And nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide-alkyne cycloaddition
Guimar?es, Tiago T.,Pinto, Maria Do Carmo F.R.,Lanza, Juliane S.,Melo, Maria N.,Do Monte-Neto, Rubens L.,De Melo, Isadora M.M.,Diogo, Emilay B.T.,Ferreira, Vitor F.,Camara, Celso A.,Valen?a, Wagner O.,De Oliveira, Ronaldo N.,Frézard, Frédéric,Da Silva Júnior, Eufranio N.
, p. 523 - 530 (2013/07/27)
Continuing our screening program for novel anti-parasite compounds, we synthesized seven 1,4-naphthoquinones coupled to 1,2,3-triazoles, five nor-β-lapachone-based 1,2,3-triazoles and ten α-lapachone-based 1,2,3-triazoles. These and other naphthoquinonoid
On the search for potential anti-Trypanosoma cruzi drugs: Synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions
Da Silva Jr., Eufranio N.,De Melo, Isadora M.M.,Diogo, Emilay B.T.,Costa, Verenice A.,De Souza Filho, José D.,Valen?a, Wagner O.,Camara, Celso A.,De Oliveira, Ronaldo N.,De Araujo, Alexandre S.,Emery, Flávio S.,Dos Santos, Marcelo R.,De Simone, Carlos A.,Menna-Barreto, Rubem F.S.,De Castro, Solange L.
, p. 304 - 312 (2012/07/27)
Five 2-hydroxy-3-substituted-aminomethyl naphthoquinones, nine 1,2,3-triazolic para-naphthoquinones, five nor-β-lapachone-based 1,2,3-triazoles, and several other naphthoquinonoid compounds were synthesized and evaluated against the infective bloodstream
