13533-32-9Relevant articles and documents
A new catalytic approach for aerobic oxidation of primary alcohols based on a Copper(I)-thiophene carbaldimines
Lagerspets, Emi,Valbonetti, Evelyn,Eronen, Aleksi,Repo, Timo
, (2021/06/03)
We report here novel Cu(I) thiophene carbaldimine catalysts for the selective aerobic oxidation of primary alcohols to their corresponding aldehydes and various diols to lactones or lactols. In the presence of the in situ generated Cu(I) species, a persistent radical (2,2,6,6-tetramethylpiperdine-N-oxyl (TEMPO)) and N-methylimidazole (NMI) as an auxiliary ligand, the reaction proceeds under aerobic conditions and at ambient temperature. Especially the catalytic system of 1-(thiophen-2-yl)-N-(4-(trifluoromethoxy)phenyl)methanimine (ligand L2) with copper(I)-iodide showed high reactivity for all kind of alcohols (benzylic, allylic and aliphatic). In the case of benzyl alcohol even 2.5 mol% of copper loading gave quantitative yield. Beside high activity under aerobic conditions, the catalysts ability to oxidize 1,5-pentadiol to the corresponding lactol (86% in 4 h) and N-phenyldiethanolamine to the corresponding morpholine derivate lactol (86% in 24 h) is particularly noteworthy.
Synthesis, Characterisation and Antibacterial Activity of some 3d-Metal Complexes with Thiophene-2-aldehyde-4-chloro/bromoaniline
Mishra,Srivastava,Srivastava, Vibhuti
, p. 487 - 488 (2007/10/03)
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