1353670-35-5Relevant articles and documents
Formation of isoxazolidines by enantioselective copper-catalyzed annulation of 2-nitrosopyridine with allylstannanes
Chatterjee, Indranil,Froehlich, Roland,Studer, Armido
, p. 11257 - 11260 (2012/02/02)
Click! Formal [3+2] cycloadditions of 2-nitrosopyridine with various allylstannanes give 4-stannyl-substituted isoxazolidines. The use of [Cu(MeCN)4]PF6, in combination with a Walphos ligand, leads to excellent enantioselectivies and high yields. With cis-2- alkenylstannanes as nucleophiles, 3-alkyl-4-stannyl-substituted isoxazolidines are formed with excellent diastereo- and enantioselectivities. Copyright