135382-79-5

Basic information

• Product Name: N-(2-Hydroxy-ethyl)-2-(pyrrolidine-1-carbonyl)-benzamide
• Synonyms: N-(2-Hydroxy-ethyl)-2-(pyrrolidine-1-carbonyl)-benzamide
• CAS NO: 135382-79-5
• Molecular Weight: 262.309
• Mol File: 135382-79-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-Hydroxy-ethyl)-2-(pyrrolidine-1-carbonyl)-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Hydroxy-ethyl)-2-(pyrrolidine-1-carbonyl)-benzamide(135382-79-5)
• EPA Substance Registry System: N-(2-Hydroxy-ethyl)-2-(pyrrolidine-1-carbonyl)-benzamide(135382-79-5)

Safety Data

• Hazardous Substances Data: 135382-79-5(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 3891-07-4 N-(2-Hydroxyethyl)phthalimide 

Relevant articles and documents

Scope of phthalimido chemistry I. Extension of utility by conversion to the opcb protecting group

The scope of the phthalimido protecting group (PhthN-) is extended by reaction with pyrrolidine. The resulting o-pyrrolidinocarbonylbenzamide ("OPCB-") represents a base/nucleophile stable derivative of the parent, which reverts to the imide form upon treatment with acid. This methodology allows utilization of this protecting group (as the OPCB form in synthetic sequences requiring basic/nucleophilic reaction conditions.