1353858-94-2

Basic information

• Product Name: 3-(5-propionylfuran-2-yl)benzoic acid
• Synonyms: 3-(5-propionylfuran-2-yl)benzoic acid
• CAS NO: 1353858-94-2
• Molecular Weight: 244.247
• Mol File: 1353858-94-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(5-propionylfuran-2-yl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(5-propionylfuran-2-yl)benzoic acid(1353858-94-2)
• EPA Substance Registry System: 3-(5-propionylfuran-2-yl)benzoic acid(1353858-94-2)

Safety Data

• Hazardous Substances Data: 1353858-94-2(Hazardous Substances Data)

Upstream product

• 179055-22-2 N-methyl-N-methoxy-5-bromofuran-2-carboxamide 
• 99769-19-4 [3-(methoxycarbonyl)phenyl]boronic acid 
• 99834-94-3 1-(5-bromofuran-2-yl)propan-1-one 
• 1353858-93-1 3-(5-propionylfuran-2-yl)benzoic acid methyl ester 
• 585-70-6 5-bromo-furan-2-carboxylic acid 

Downstream Products

• 1353858-95-3 1-{5-[3-(4-methyl[1,4]diazepane-1-carbonyl)phenyl]furan-2-yl}propan-1-one 
• 1353859-03-6 5-chloro-3-[1-{5-[3-(4-methyl-[1,4]diazepane-1-carbonyl)phenyl]furan-2-yl}propylidene]-1,3-dihydroindol-2-one 

Relevant articles and documents

Discovery of CX-6258. A potent, selective, and orally efficacious pan-pim kinases inhibitor

Structure-activity relationship analysis in a series of 3-(5-((2-oxoindolin-3-ylidene)methyl)furan-2-yl)amides identified compound 13, a pan-Pim kinases inhibitor with excellent biochemical potency and kinase selectivity. Compound 13 exhibited in vitro synergy with chemotherapeutics and robust in vivo efficacy in two Pim kinases driven tumor models.