135387-91-6

Basic information

• Product Name: (S)-4-Benzyl-3-[2-(3,5-bis-benzyloxy-phenyl)-acetyl]-oxazolidin-2-one
• Synonyms: (S)-4-Benzyl-3-[2-(3,5-bis-benzyloxy-phenyl)-acetyl]-oxazolidin-2-one
• CAS NO: 135387-91-6
• Molecular Weight: 507.586
• Mol File: 135387-91-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-4-Benzyl-3-[2-(3,5-bis-benzyloxy-phenyl)-acetyl]-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-Benzyl-3-[2-(3,5-bis-benzyloxy-phenyl)-acetyl]-oxazolidin-2-one(135387-91-6)
• EPA Substance Registry System: (S)-4-Benzyl-3-[2-(3,5-bis-benzyloxy-phenyl)-acetyl]-oxazolidin-2-one(135387-91-6)

Safety Data

• Hazardous Substances Data: 135387-91-6(Hazardous Substances Data)

Upstream product

• 79762-35-9 methyl 2-(3,5-bis(benzyloxy)-2-formylphenyl)acetate 
• 28917-44-4 3,5-dibenzyloxylbenzoyl chloride 
• 50513-72-9 (3,5-di-benzyloxy)benzoic acid benzyl ester 
• 2732-96-9 3,5-dibenzyloxyphenylacetic acid 
• 28917-43-3 3,5-dibenzyloxybenzoic acid 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 52144-91-9 3,5-bis(benzyloxy)diazoacetophenone 
• 100-44-7 benzyl chloride 

Downstream Products

• 312328-55-5 (S)-Alloc-Dhpg(OBn)2-OH 
• 312328-68-0 [(S)-2-((S)-4-Benzyl-2-oxo-oxazolidin-3-yl)-1-(3,5-bis-benzyloxy-phenyl)-2-oxo-ethyl]-carbamic acid allyl ester 
• 312328-67-9 (S)-3-[(S)-2-Azido-2-(3,5-bis-benzyloxy-phenyl)-acetyl]-4-benzyl-oxazolidin-2-one 
• 135387-94-9 C₄₇H₅₂N₄O₇S 

Relevant articles and documents

Solid-phase synthesis using (Allyloxy)carbonyl(Alloc) chemistry of a putative heptapeptide intermediate in vancomycin biosynthesis containing m-chloro-3-hydroxytyrosine

A convenient method for the solid-phase synthesis of putative linear heptapeptide intermediates in vancomycin biosynthesis is described, in particular, the heptapeptide D-Leu-Cyt-L-Asn-Hpg-Hpg-Cyt'-Dhpg (Cyt = (2R,3R)-m-chloro-3-hydroxytyrosine, Hpg = (R)-2-(p-hydroxyphenyl)glycine, Cyt' = (2S,3R)-m-chloro-3-hydroxytyrosine and Dhpg = (S)-2-(3,5-dihydroxyphenyl)glycine). The synthesis was performed on chlorotrityl resin and employed the (allyloxy)carbonyl protecting group for temporary N(α) protection during peptide-chain assembly.