1353993-49-3Relevant articles and documents
A N - propylene carbonyl piperidine derivatives for the preparation of
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Paragraph 0063; 0064; 0065, (2018/10/11)
The invention relates to a method for preparing an N-propylene carbonyl piperidine derivative, in particular to a new midbody for preparing ibrutinib, a preparation method of the new midbody and a method for preparing the ibrutinib, and belongs to the technical field of pharmacy. The method relates to a reaction as specified in the following formula (please see the specification for the formula). The method is easy to operate, capable of lowering cost and beneficial to industrial production.
5-AMINO-4-CARBAMOYL-PYRAZOLE COMPOUNDS AS SELECTIVE AND IRREVERSIBLE T790M OVER WT-EGFR KINASE INHIBITORS AND USE THEREOF????
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Paragraph 0086, (2016/03/13)
Disclosed are compounds of Formula (I), pharmaceutical compositions comprising the same, processes for the preparation thereof, and the use thereof.
HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS
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Paragraph 0107; 0108; 0109, (2014/03/21)
The present invention encompasses compounds of the formula (I) wherein the groups A, Cy, X1 and Y are defined herein, which are suitable for the treatment of diseases related to BTK, process of making, pharmaceutical preparations which contain compounds and their methods of use.