135439-45-1

Basic information

• Product Name: Benzyl-(1-benzyl-2-oxo-2λ⁵-[1,3,2]diazaphospholidin-2-yl)-amine
• Synonyms: Benzyl-(1-benzyl-2-oxo-2λ⁵-[1,3,2]diazaphospholidin-2-yl)-amine
• CAS NO: 135439-45-1
• Molecular Weight: 301.328
• Mol File: 135439-45-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzyl-(1-benzyl-2-oxo-2λ⁵-[1,3,2]diazaphospholidin-2-yl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyl-(1-benzyl-2-oxo-2λ⁵-[1,3,2]diazaphospholidin-2-yl)-amine(135439-45-1)
• EPA Substance Registry System: Benzyl-(1-benzyl-2-oxo-2λ⁵-[1,3,2]diazaphospholidin-2-yl)-amine(135439-45-1)

Safety Data

• Hazardous Substances Data: 135439-45-1(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 3287-99-8 benzylamine hydrochloride 
• 69510-41-4 N-benzylphosphoroamidodichloridate 
• 4152-09-4 N-benzylethylenediamine 

Relevant articles and documents

Phosphoric amides. Part 11. Intramolecular reactivity of phosphorotriamidates

Five N-(2-chloroethyl)phosphorotriamidates, (RNH)2P(O)NHCH2CH2Cl, have been synthesized, and their behavior under strongly basic conditions was studied.For N-alkyl derivatives (R = Me, PhCH2), base-promoted intramolecular displacement of chloride yielded the N-phosphorylated aziridine, (RNH)2P(O)NC2H4, as the exclusive cyclization product.For N-aryl derivatives (R = Ar), both the aziridine and the 1,3,2-diazaphospholidine, RNHP(O)NHCH2CH2NR, products could be obtained in comparable yields.The N-aromatic cyclic products are mutually interconvertible; 1,3,2-diazaphospholidines rearrange to the corresponding aziridines upon treatment with base, while bromide ions catalyze the reverse isomerization. Key words: phosphoramidates acidity, N-phosphorylated aziridines - 1,3,2-diazaphospholidines isomerization, 1,3 vs. 1,5 cyclization.