1354548-49-4

Basic information

• Product Name: 1-azabicyclo[2.2.2]oct-8-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate fumarate
• CAS NO: 1354548-49-4
• Molecular Weight: 478.545
• Mol File: 1354548-49-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-azabicyclo[2.2.2]oct-8-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate fumarate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-azabicyclo[2.2.2]oct-8-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate fumarate(1354548-49-4)
• EPA Substance Registry System: 1-azabicyclo[2.2.2]oct-8-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate fumarate(1354548-49-4)

Safety Data

• Hazardous Substances Data: 1354548-49-4(Hazardous Substances Data)

Upstream product

• 110-17-8 (2E)-but-2-enedioic acid 
• 242478-37-1 solifenacin 
• 22990-19-8 (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 180468-42-2 (S)-N-carboxylic acid ethyl ester-1-phenyl-1,2,3,4-tetrahydroisoquinoline 

Downstream Products

• 1262506-09-1 (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl 3,4-dihydro-1-phenyl-2(1H)-isoquinoline carboxylate succinate 

Relevant articles and documents

SOLIFENACIN SALTS

The invention concerns fumarate salts of solifenacin, as well as pharmaceutical compositions comprising fumarate salts of solifenacin. The invention furthermore concerns a process for preparing solifenacin and salts thereof. The fumarate salt provides improved properties over the known solifenacin salts, especially in terms of its stability. The novel process for its preparation is furthermore improved over known processes for preparing solifenacin in that it provides a higher yield and recovers a greater amount of starting material.