1354688-43-9

Basic information

• Product Name: C₃₇H₃₉N₂O₃⁽¹⁺⁾*ClO₄^(1-)
• Synonyms: C₃₇H₃₉N₂O₃⁽¹⁺⁾*ClO₄^(1-)
• CAS NO: 1354688-43-9
• Molecular Weight: 659.179
• Mol File: 1354688-43-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₃₇H₃₉N₂O₃⁽¹⁺⁾*ClO₄^(1-)(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₇H₃₉N₂O₃⁽¹⁺⁾*ClO₄^(1-)(1354688-43-9)
• EPA Substance Registry System: C₃₇H₃₉N₂O₃⁽¹⁺⁾*ClO₄^(1-)(1354688-43-9)

Safety Data

• Hazardous Substances Data: 1354688-43-9(Hazardous Substances Data)

Upstream product

• 84-83-3 1,3,3-trimethyl-2-formylmethyleneindoline 
• 108-94-1 cyclohexanone 
• 5809-23-4 2'-Carboxy-4-diethylamino-2-hydroxybenzophenon 

Downstream Products

• 1374637-02-1 C₄₁H₄₂N₃O₅⁽¹⁺⁾ 
• 1618670-90-8 C₄₃H₄₄N₄O₂ 

Relevant articles and documents

PH-activatable near-infrared fluorescent probes for detection of lysosomal pH inside living cells

Four near-infrared fluorescent probes (A, B, C and D) have been synthesized, characterized, and evaluated for detection of lysosomal pH inside living cells. The fluorescent probes display highly sensitive and selective fluorescent response to acidic pH as the acidic pH results in drastic structural changes from spirocyclic (non-fluorescent) forms to ring-opening (fluorescent) forms of the fluorescent probes. The fluorescence intensities of the fluorescent probes (B, C and D) increase significantly by more than 200-fold from pH 7.4 to 4.2. The fluorescent probe D bearing the N-(2-hydroxyethyl) ethylene amide residue possesses the advantages of high sensitivity, excellent photostability, good cell membrane permeability, strong pH dependence, and low auto-fluorescence background. It has been successfully applied to selectively stain lysosomes and detect lysosomal pH changes inside normal endothelial and breast cancer cells. This journal is the Partner Organisations 2014.