1355083-83-8Relevant articles and documents
The behaviour of Bis(diphenylphosphino)alkanes towards different active centres
Ewies, Ewies F.,El-Sayed, Naglaa F.,Boulos, Leila S.
, p. 417 - 421 (2016)
Benzophenones (diarylmethanones) are important starting materials in the synthesis and preparation of organic compounds such as heat-resistant resins, various drugs, and natural products.1-7 1,1′-(Azodicarbonyl)dipiperidine has different pharmacological and biological activities.8-13 The versatility of isatin (1H-indole-2,3-dione) in synthetic organic chemistry is shown in its biological and pharmacological properties and its extensive use in organic synthesis.14 Moreover, quinoxaline 1,4-di-N-oxide is a building block that has a broad range of biological applications.15 Bis(diphenylphosphino)alkanes have been reported as anticancer agents.16-20The useful applications of these starting materials, coupled with our interest in organophosphorus chemistry,21-25 encouraged us to synthesise new organophosphorus compounds and to identify the preferred site of attack of these compounds. We sought to obtain the target compounds by reacting bis(diphenylphosphino) alkanes 1a-c with some different organic compounds; namely, benzophenone2, 1,1′-(azodicarbonyl)dipiperidine (ADDP, 3), isatin 4a and 4b, and quinoxaline 1,4-di-N-oxide 5 (Scheme 1).
