135578-08-4

Basic information

• Product Name: 1,3-Dioxane-4,6-dione, 2,2-dimethyl-5-(2-oxo-2-phenylethyl)-
• CAS NO: 135578-08-4
• Molecular Formula: C14H14O5
• Molecular Weight: 262.262
• Mol File: 135578-08-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxane-4,6-dione, 2,2-dimethyl-5-(2-oxo-2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxane-4,6-dione, 2,2-dimethyl-5-(2-oxo-2-phenylethyl)-(135578-08-4)
• EPA Substance Registry System: 1,3-Dioxane-4,6-dione, 2,2-dimethyl-5-(2-oxo-2-phenylethyl)-(135578-08-4)

Safety Data

• Hazardous Substances Data: 135578-08-4(Hazardous Substances Data)

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 1011-46-7 6-phenyl-2,3,4,5-tetrahydropyridazin-3-one 
• 17812-07-6 Benzoylacrylic acid 
• 135578-09-5 2,2-dimethyl-5-phenacyl-5-chloro-1,3-dioxane-4,6-dione 
• 1955-39-1 5-phenyl-3H-furan-2-one 

Relevant articles and documents

MELDRUM'S ACID - A REAGENT FOR THE SYNTHESIS OF UNSATURATED γ-LACTONES AND β-ACYLACRYLIC ACIDS

The thermal cyclization of 2,2-dimethyl-5-(2-aryl-2-oxoethyl)-1,3-dioxan-4,6-diones forms 5-aryl-β,γ-butenolides.Regioselective chlorination of 2,2-dimethyl-5--1,3-dioxane-4,6-diones by SO2Cl2 gives the 5-chloro derivatives, thes

Monoalkylation studies with Meldrum's acid

A general procedure for the monoalkylation of Meldrum's acid (1) is described.Meldrum's acid anion in DMF is slowly added to alkyl halides in DMF to give monoalkylated products.Lower primary as well as highly reactive halides give a mixture of mono- and b