13563-36-5

Basic information

• Product Name: 3(2H)-Pyridazinone, 4-amino-2-methyl-
• Synonyms: 2-Methyl-4-amino-3(2H)-pyridazinon;5-amino-1-methyl-6-pyridazone;4-amino-2-methyl-2H-pyridazin-3-one;2-Methyl-4-amino-6-methoxy-3(2H)-pyridazinon;4-amino-2-methylpyridazin-3-one
• CAS NO: 13563-36-5
• Molecular Formula: C5H7N3O
• Molecular Weight: 125.13
• Mol File: 13563-36-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3(2H)-Pyridazinone, 4-amino-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Pyridazinone, 4-amino-2-methyl-(13563-36-5)
• EPA Substance Registry System: 3(2H)-Pyridazinone, 4-amino-2-methyl-(13563-36-5)

Safety Data

• Hazardous Substances Data: 13563-36-5(Hazardous Substances Data)

Upstream product

• 1266244-67-0 (2-methyl-3-oxo-2,3-dihydro-pyridazin-4-ylamino)-acetate tert-butyl ester 
• 1266244-68-1 C₁₁H₁₆ClN₃O₃ 
• 14628-57-0 4-chloro-5-methoxy-2-methyl-2H-pyridazin-3-one 
• 933-76-6 4,5-dichloro-2-methyl-3(2H)-pyridazinone 

Downstream Products

• 127755-60-6 5-(2-bromobenzamido)-1-methyl-6-pyridazone 
• 1266245-57-1 4-(2-chloro-5-trifluoromethyl-phenoxy)-piperidine-1-carboxylic acid (2-methyl-3-oxo-2,3-dihydro-pyridazin-4-yl)-amide 
• 1266245-05-9 4-{2-[4-(5-fluoro-2-trifluoromethyl-phenoxy)-piperidin-1-yl]-2-oxo-ethylamino}-2-methyl-2H-pyridazin-3-one 
• 1266245-06-0 4-{2-[4-(3-fluoro-5-trifluoromethyl-phenoxy)-piperidin-1-yl]-2-oxo-ethylamino}-2-methyl-2H-pyridazin-3-one 

Relevant articles and documents

An efficient and practical method for the synthesis of 1-(2,6- difluorobenzoyl)-3-(2-alkyl-3-oxopyridazin-4-yl)ureas as potential chitin synthesis inhibitors

A mild and efficient method for the synthesis of 4-amino-3(2H)- pyridazinones from their corresponding 4,5-dichloropyridazinones under microwave-assisted conditions is described. A series of novel chitin synthesis inhibitors, benzoylphenylureas containing

DERIVATIVES OF 2H PYRIDAZIN- 3 -ONES, THEIR PREPARATION AND THEIR USE AS SCD-1 INHIBITORS

The present invention concerns compounds of general formula (I) characterized in that (formula 1) wherein, in particular: -R1 represents one or more groups such as: trif luoromethyl, halogen such as F, C1, -when n=m=1, W represents CH then Y represents oxygen, -U represents: ? either - (C=O) CH2NH- and is branched at position 4 of pyridazinone, then R2 represents H, ? or -(C=O)NH- and U is branched at positions (4), (5) or (6) of pyridazinone, then R2 represents H, - R3 represents a hydrogen or methyl and the addition salts with pharmaceutically acceptable bases and acids and the different isomers, and their mixtures in any proportion for use as SCD-1 enyzme inhibitors for the treatment of obesitz, tzpe-2 diabetes and lipid disorders.