135631-91-3

Basic information

• Product Name: 6-bromo-1,2,3,4-tetrahydro-4,4-dimethylquinoline hydrochloride
• Synonyms: 6-bromo-1,2,3,4-tetrahydro-4,4-dimethylquinoline hydrochloride;6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinoline, HCl;4-diMethylquinoline hydrochloride;4-tetrahydro-4;6-broMo-1;6-BroMo-1,2,3,4-tetrahydro-4,4-diMethyl-quinoline HCl;6-BroMo-1,2,3,4-tetrahydro-4,4-diMethylquinoline;CAS:135631-91-3
• CAS NO: 135631-91-3
• Molecular Formula: C₁₁H₁₄BrN
• Molecular Weight: 276.6
• Product Categories: CHIRAL CHEMICALS
• Mol File: 135631-91-3.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 338 °C at 760 mmHg
• Flash Point: 158.2 °C
• Appearance: /
• Density: 1.285g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: Room temperature.
• PKA: 4.33±0.40(Predicted)
• CAS DataBase Reference: 6-bromo-1,2,3,4-tetrahydro-4,4-dimethylquinoline hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 6-bromo-1,2,3,4-tetrahydro-4,4-dimethylquinoline hydrochloride(135631-91-3)
• EPA Substance Registry System: 6-bromo-1,2,3,4-tetrahydro-4,4-dimethylquinoline hydrochloride(135631-91-3)

Safety Data

• Hazardous Substances Data: 135631-91-3(Hazardous Substances Data)

Usage

General Description

6-bromo-1,2,3,4-tetrahydro-4,4-dimethylquinoline hydrochloride is a chemical compound that is commonly used in pharmaceutical research and drug development. It is a hydrochloride salt form of the quinoline derivative and is known for its potential therapeutic effects. 6-bromo-1,2,3,4-tetrahydro-4,4-dimethylquinoline hydrochloride has shown promising biological activities, including anti-inflammatory and analgesic properties, making it a subject of interest for potential drug candidates. Its molecular structure and unique properties make it a valuable chemical for further study and potential application in the pharmaceutical industry.

InChI:InChI=1/C11H14BrN/c1-11(2)5-6-13-10-4-3-8(12)7-9(10)11/h3-4,7,13H,5-6H2,1-2H3

Upstream product

• 135631-90-2 4,4-dimethyl-6-bromo-2-oxo-1,2,3,4-tetrahydroquinoline 
• 3350-78-5 3,3-Dimethylacryloyl chloride 
• 106-40-1 4-bromo-aniline 
• 135631-89-9 N-(3,3'-dimethylacryoloyl)-4-bromoaniline 

Downstream Products

• 263550-60-3 tert-butyl 6-bromo-4,4-dimethyl-3,4-dihydroquinoline-1(2H)-carboxylate 
• 1187933-54-5 tert-butyl 6-amino-4,4-dimethyl-3,4-dihydroquinoline-1(2H)-carboxylate 
• 1201684-58-3 4,4-dimethyl-6-(4-trifluoromethyl-phenyl)-1,2,3,4-tetrahydro-quinoline 
• 198696-06-9 4-(1-Heptyl-4,4-dimethyl-1,2,3,4-tetrahydro-quinolin-6-ylethynyl)-benzoic acid ethyl ester 

Relevant articles and documents

Inhibitors Targeting STAT5 Signaling in Myeloid Leukemias: New Tetrahydroquinoline Derivatives with Improved Antileukemic Potential

Signal transducers and activators of transcription 5A and 5B (STAT5A and STAT5B) are two closely related STAT family members that are crucial downstream effectors of tyrosine kinase oncoproteins such as FLT3-ITD in acute myeloid leukemia (AML) and BCR-ABL

CHROMAN-SUBSTITUTED, TETRAHYDROQUINOLINE-SUBSTITUTED AND THIOCHROMAN-SUBSTITUTED HETEROAROTINOIDS AS ANTI-CANCER AGENTS

Chemical compounds that inhibit cancer cell growth are provided. The compounds are heteroarotinoids and derivatives thereof with oxygen, nitrogen or sulfur in chroman systems, tetrahydroquinoline systems, and tetrahydrothiochroman systems.

5-[PHENYL-TETRAHYDRONAPHTHALENE-2-YL DIHYDRONAPHTHALEN-2-YL AND HETEROARYL-CYCLOPROPYL]-PENTADIENOIC ACID DERIVATIVES HAVING SERUM GLUCOSE REDUCING ACTIVITY

Compounds of the formula where the variables have the meaning defined in the specification are capable of reducing serum glucose levels in diabetic mammals without the undesirable side effects of reducing serum thyroxine levels and transiently increasing triglyceride levels.