135637-09-1

Basic information

• Product Name: (1S,2R)-<1-2H>-1-phenylpropan-2-ol
• Synonyms: (1S,2R)-<1-2H>-1-phenylpropan-2-ol
• CAS NO: 135637-09-1
• Molecular Weight: 137.186
• Mol File: 135637-09-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (1S,2R)-<1-2H>-1-phenylpropan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-<1-2H>-1-phenylpropan-2-ol(135637-09-1)
• EPA Substance Registry System: (1S,2R)-<1-2H>-1-phenylpropan-2-ol(135637-09-1)

Safety Data

• Hazardous Substances Data: 135637-09-1(Hazardous Substances Data)

Upstream product

• 23355-97-7 1-phenylpropylene oxide 
• 14212-54-5 (+)-(R,R)-β-methylstyrene oxide 
• 135561-74-9 Toluene-4-sulfonic acid (1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl ester 
• 623575-61-1 1-(phenylseleno)-1-phenylpropan-2-ol 
• 766-90-5 cis-1-phenyl-1-propylene 
• 563-52-0 2-chloro-3-butene 
• 28557-00-8 phenylzinc chloride 
• 74-88-4 methyl iodide 
• 100-52-7 benzaldehyde 
• 40421-52-1 (1R,2S)-1-phenylpropane-1,2-diol 

Downstream Products

• 80150-93-2 threo-(1-⁽²⁾H)-1-phenyl-2-dimethylaminopropane 
• 66432-33-5 threo-(1-⁽²⁾H)-1-phenyl-2-aminopropane 
• 80150-91-0 C₁₂H₁₉⁽²⁾HN⁽¹⁺⁾*Cl^(1-) 
• 90159-11-8 C₁₅H₁₃⁽²⁾HN₂O₄S 
• 90159-11-8 C₁₅H₁₃⁽²⁾HN₂O₄S 
• 90159-14-1 C₁₅H₁₅⁽²⁾HSe 
• 90159-14-1 (⁽²⁾H₁-1) phenyl-1 phenylselenyl-2 propane threo 
• 90159-08-3 C₁₅H₁₅⁽²⁾HS 
• 90159-08-3 phenyl <((2)H₁-1) phenyl-1 propyl-2> thioether threo 
• 80150-96-5 (⁽²⁾H₁-1) phenyl-1 tosyl-2 propane 
• 80150-96-5 C₁₆H₁₇⁽²⁾HO₃S 

Relevant articles and documents

Enantiomerically Enriched α-Borylzinc Reagents by Nickel-Catalyzed Carbozincation of Vinylboronic Esters

In this paper is described a synthesis of enantiomerically enriched, configurationally stable organozinc reagents by catalytic enantioselective carbozincation of a vinylboronic ester. This process furnishes enantiomerically enriched α-borylzinc intermediates that are shown to undergo stereospecific reactions, producing enantioenriched secondary boronic ester products. The properties of the intermediate α-borylzinc reagent are probed and the synthetic utility of the products is demonstrated by application to the synthesis of (-)-aphanorphine and (-)-enterolactone.

Efficient Control of the Stereoselectivity in Reactions of 2-Oxy-Substituted Benzylic Radicals

The stereoselectivity in reactions of 2-oxy-substituted radicals of type B was investigated.As expected, minimization of allylic 1,3-starin was the major controlling factor.Under standard conditions, only a modest level of stereoselectivity was observed.E

Weak Base Promoted β-Elimination Reactions in 1-Phenyl-1-propyl Derivatives. Evidence for an Intermediate in the E2C Reaction

We describe the observation of a nucleophile trigger mechanism in the case of the weak base promoted β-elimination (E2C process) and suggest permutational isomerism of TBP intermediates.Weak bases, namely, bromide and fluoride ions, bring about elimination in a bent transition state to which only a small fraction of a covalent bond to the nucleophile-base and some leaving group departure must be achieved in an orienting intermediate.These studies provide evidence for a TBP structure surrounding C-α in the 1-phenyl-1-propyl system and attribute the equal availability of abstractable H and D of both diastereoisomers to the action of the promoter bases.