1356998-77-0

Basic information

• Product Name: N-(4-(4-fluorophenyl)-6-isopropyl-5-(prop-1-enyl)pyrimidin-2-yl)-N-methylmethanesulfonamide
• Synonyms: N-(4-(4-fluorophenyl)-6-isopropyl-5-(prop-1-enyl)pyrimidin-2-yl)-N-methylmethanesulfonamide
• CAS NO: 1356998-77-0
• Molecular Weight: 363.456
• Mol File: 1356998-77-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(4-(4-fluorophenyl)-6-isopropyl-5-(prop-1-enyl)pyrimidin-2-yl)-N-methylmethanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-(4-fluorophenyl)-6-isopropyl-5-(prop-1-enyl)pyrimidin-2-yl)-N-methylmethanesulfonamide(1356998-77-0)
• EPA Substance Registry System: N-(4-(4-fluorophenyl)-6-isopropyl-5-(prop-1-enyl)pyrimidin-2-yl)-N-methylmethanesulfonamide(1356998-77-0)

Safety Data

• Hazardous Substances Data: 1356998-77-0(Hazardous Substances Data)

Upstream product

• 1356998-76-9 N-(5-allyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide 
• 1356998-75-8 5-allyl-4-(4-fluorophenyl)-6-isopropyl-N-methylpyrimidin-2-amine 
• 1356998-74-7 2-allyl-1-(4-fluorophenyl)-4-methylpentane-1,3-dione 
• 114433-94-2 1-(4-Fluorophenyl)-3-isopropylpropan-1,3-dione 

Downstream Products

• 147118-37-4 N-[4-(4-fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES FOR THE SYNTHESIS OF STATINS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF

The invention relates to commercially viable process for the synthesis of key intermediates for the preparation of statins, in particular Rosuvastatin and Pitavastatin or respective pharmaceutically acceptable salts thereof. A new simple and short synthetic route for key intermediates is presented which benefits from the use of cheap and readily available starting materials, by which the conventionally most frequently used DIBAL-H as reducing agent can be avoided.