135703-82-1

Basic information

• Product Name: {4-[tert-Butoxycarbonylamino-((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-methyl]-thiazol-2-yl}-carbamic acid benzyl ester
• CAS NO: 135703-82-1
• Molecular Weight: 632.822
• Mol File: 135703-82-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {4-[tert-Butoxycarbonylamino-((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-methyl]-thiazol-2-yl}-carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {4-[tert-Butoxycarbonylamino-((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-methyl]-thiazol-2-yl}-carbamic acid benzyl ester(135703-82-1)
• EPA Substance Registry System: {4-[tert-Butoxycarbonylamino-((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-methyl]-thiazol-2-yl}-carbamic acid benzyl ester(135703-82-1)

Safety Data

• Hazardous Substances Data: 135703-82-1(Hazardous Substances Data)

Upstream product

• 60845-81-0 ethyl 2-amino-α-(hydroxyimino)-4-thiazole acetate 
• 92592-16-0 ethyl α-(2-benzyloxycarbonylaminothiazol-4-yl)-α-(t-butoxycarbonylamino)acetate 
• 85208-11-3 ethyl α-amino-α-(2-aminothiazol-4-yl)acetate dihydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 60846-29-9 ethyl 2-amino-α-(N-(t-butoxycarbonyl)amino)-4-thiazoleacetate 
• 104882-45-3 (S)-2-amino-1-cyclohexyl-(R)-3,(S)-4-dihydroxy-6-methylheptane hydrochloride 
• 85208-14-6 α-(2-benzyloxycarbonylaminothiazol-4-yl)-α-(t-butoxycarbonylamino)acetic acid 

Downstream Products

• 135704-13-1 (4-{((1S,2R,3S)-1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-[(S)-2-(morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-methyl}-thiazol-2-yl)-carbamic acid benzyl ester 
• 135703-97-8 <1S-<1R*,2S*,3R*>>-2-amino-N-<1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl>-α-<<2-<(4-morpholinylsulfonyl)amino>-1-oxo-3-phenylpropyl>amino>-3-thiazoleacetamide 
• 135703-83-2 {4-[Amino-((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-methyl]-thiazol-2-yl}-carbamic acid benzyl ester; hydrochloride 

Relevant articles and documents

Structure-Activity Relationships of a Series of 2-Amino-4-thiazole-Containing Renin Inhibitors

A series of renin inhibitors was synthesized that contained a 2-amino-4-thiazolyl moiety at the P2 position.These derivatives are potent inhibitors of monkey renin in vitro and are selective in that they only weakly inhibit the closely related