1357170-63-8Relevant articles and documents
A Versatile Ru(II)-NNP Complex Catalyst for the Synthesis of Multisubstituted Pyrroles and Pyridines
Chai, Huining,Wang, Liandi,Liu, Tingting,Yu, Zhengkun
, p. 4936 - 4942 (2017)
A pincer-type Ru(II)-NNP complex bearing a pyrazolyl-(NH-PtBu2)-pyridine ligand was synthesized and structurally characterized by NMR, IR, elemental analysis, and X-ray single-crystal crystallographic determinations, which efficiently catalyzed the synthesis of multisubstituted pyrroles and pyridines by means of the reactions of secondary alcohols and β- or γ-amino alcohols through deoxygenation and selective C-N and C-C bond formation. The coupling reactions took place with 0.3 mol % catalyst loading and tolerated diverse functional groups. The present work provides an alternative method to construct highly active transition-metal complex catalysts from readily available ligands.
Switchable reactivity between vinyl azides and terminal alkyne by nano copper catalysis
Cen, Jinghe,Wu, Yaodan,Li, Jianxiao,Huang, Liangbin,Wu, Wanqing,Zhu, Zhongzhi,Yang, Shaorong,Jiang, Huanfeng
, p. 2090 - 2094 (2019/03/26)
A novel nano copper-catalyzed substrate-dependent chemodivergent transformation of vinyl azides with a terminal alkyne is disclosed. 2,5-Disubstituted pyrroles were selectively obtained in high yield with aryl alkynes and aliphatic alkynes, whereas 2,3,4-trisubstituted pyrroles were formed with silylated alkynes. This switchable method provides a controllable and facile access to both multisubstituted pyrrole scaffolds with high efficiency, excellent regioselectivity, and good functional group compatibility.
