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135729-75-8

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135729-75-8 Usage

Description

PALONOSETRON HCL, also known as Aloxi, is a selective 5-HT3 receptor antagonist that belongs to the class of antiemetic drugs. It is an off-white solid with potent antiemetic properties, making it a valuable pharmaceutical compound for managing nausea and vomiting associated with various medical conditions.

Uses

Used in Pharmaceutical Industry:
PALONOSETRON HCL is used as an antiemetic agent for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It works by blocking the action of serotonin, a neurotransmitter that can cause nausea and vomiting when released in large amounts during chemotherapy. By inhibiting the 5-HT3 receptors, PALONOSETRON HCL effectively reduces the severity and frequency of CINV, improving the quality of life for patients undergoing cancer treatment.
Additionally, PALONOSETRON HCL may also be used in the management of postoperative nausea and vomiting (PONV) and radiotherapy-induced nausea and vomiting (RINV), further demonstrating its versatility as an antiemetic agent in various medical applications.

Check Digit Verification of cas no

The CAS Registry Mumber 135729-75-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,7,2 and 9 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 135729-75:
(8*1)+(7*3)+(6*5)+(5*7)+(4*2)+(3*9)+(2*7)+(1*5)=148
148 % 10 = 8
So 135729-75-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H24N2O/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20/h2,4,6,13,15,17H,1,3,5,7-12H2/t15-,17+/m1/s1

135729-75-8 Well-known Company Product Price

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  • (1492211)  Palonosetron Enantiomer  United States Pharmacopeia (USP) Reference Standard

  • 135729-75-8

  • 1492211-15MG

  • 14,500.98CNY

  • Detail

135729-75-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (R,R)-Palonosetron Hydrochloride

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:135729-75-8 SDS

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