13573-34-7Relevant articles and documents
Direct synthesis of 2,4,5-trisubstituted imidazoles and di/tri-substituted pyrimidines via cycloadditions of α,β-unsaturated ketones/aldehydes and N′-hydroxyl imidamides
Wu, Ping,Zhang, Xueguo,Chen, Baohua
, p. 1103 - 1107 (2019)
An efficient route for the synthesis of 5-acetylimidazoles and di/trisubstituted pyrimidines via iron-catalyzed cross-dehydrogenative coupling (CDC), with excellent tolerance and yields, has been developed. In this report, α,β-unsaturated aldehydes/ketones and N′-hydroxyl imidamides undergo [3+2] and [3+3] cycloadditions in two processes, involving iron-mediated Michael reaction, Robinson Annulation and 1,5-electrocyclization.
Preparation method of 2,4,6-triaryl-substituted-pyrimidine compounds
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Paragraph 0056-0059, (2019/10/01)
The invention discloses a preparation method of 2,4,6-triaryl-substituted-pyrimidine compounds. The preparation method includes the following steps that aromatic aldehyde compounds shown in the formula (I), aromatic ketone compounds shown in the formula (
Secondary amines immobilized inside magnetic mesoporous materials as a recyclable basic and oxidative heterogeneous nanocatalyst for the synthesis of trisubstituted pyrimidine derivatives
Aryan, Reza,Beyzaei, Hamid,Nojavan, Masoomeh,Dianatipour, Tahereh
, p. 4417 - 4431 (2016/07/06)
A novel magnetic MCM-41 nanocomposite-based catalyst is reported for the first time in the multicomponent synthesis of trisubstituted pyrimidines in which piperazine is immobilized inside the mesochannels of magnetic MCM-41 as an organic base (α-Fe2