135748-35-5 Usage
General Description
4-Chloro-2,5-difluorobenzenitrile, also known as CAS Number 105137-08-1, is a chemical compound that belongs to the class of organofluorines, specifically difluorobenzenes. It is identified as a pale yellow to dark brown solid substance, often used in a wide variety of scientific and pharmaceutical applications due to its chemical stability. 4-CHLORO-2,5-DIFLUOROBENZONITRILE is synthesized in the lab and is not naturally occurring. Known for its low reactivity with water, it is also considered a derivative of benzonitriles. Safety precautions should be observed when handling 4-Chloro-2,5-difluorobenzenitrile as it may be harmful if inhaled or ingested and may cause skin and eye irritation. It should be stored under cool and dry conditions, away from sources of ignition.
Check Digit Verification of cas no
The CAS Registry Mumber 135748-35-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,7,4 and 8 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 135748-35:
(8*1)+(7*3)+(6*5)+(5*7)+(4*4)+(3*8)+(2*3)+(1*5)=145
145 % 10 = 5
So 135748-35-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H2ClF2N/c8-5-2-6(9)4(3-11)1-7(5)10/h1-2H
135748-35-5Relevant articles and documents
Discovery and biological evaluation of novel 4-amino-2-phenylpyrimidine derivatives as potent and orally active GPR119 agonists
Negoro, Kenji,Yonetoku, Yasuhiro,Misawa-Mukai, Hana,Hamaguchi, Wataru,Maruyama, Tatsuya,Yoshida, Shigeru,Takeuchi, Makoto,Ohta, Mitsuaki
, p. 5235 - 5246 (2012/11/07)
Novel 4-amino-2-phenylpyrimidine derivatives were synthesized and evaluated as GPR119 agonists. Optimization of the substituents on the phenyl ring at the 2-position and the amino group at the 4-position led to the identification of 3,4-dihalogenated and
