135782-25-1Relevant articles and documents
Oligopetides with cyclic proline-analogous amino acids
-
, (2008/06/13)
The invention relates to compounds of the formula I STR1 in which A denotes an optionally substituted radical from the series comprising alkyl, acyl, cycloalkyl, aryl and heteroaryl; Cyc represents an optionally substituted heterocyclic carbonyl compound; D represents NH, NCH3, O or CH2 ; E represents CHOH, CO, SO or optionally N-substituted C=NH; F represents O, NH, NCH3 or a bond; R4 denotes an optionally substituted radical from the series comprising alkyl, cycloalkyl, aryl and heteroaryl; and R8 denotes hydrogen or optionally substituted alkyl, to a process for the preparation thereof, and to the use thereof as inhibitors of prolyl hydroxylase.
The synthesis of 2-morpholine carboxylic acid derivatives and their elaboration to 1-aza-4-oxabicyclo[3.3.1]nonan-6-one
King,Martin
, p. 2281 - 2284 (2007/10/19)
Two syntheses of novel 2-morpholine carboxylic acid derivatives are described. The esters were converted into 1-aza-4-oxabicyclo[3.3.1]nonan-6-one, the first example of this ring system, which was further elaborated to the ortho-methoxy benzamide derivative (2).