1358517-02-8

Basic information

• Product Name: (1S,4R)-3-diphenylphosphino-4-diphenylphosphoryl-cyclohex-2-enyloxy(tert-butyl)diphenylsilane
• CAS NO: 1358517-02-8
• Molecular Weight: 720.903
• Mol File: 1358517-02-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,4R)-3-diphenylphosphino-4-diphenylphosphoryl-cyclohex-2-enyloxy(tert-butyl)diphenylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,4R)-3-diphenylphosphino-4-diphenylphosphoryl-cyclohex-2-enyloxy(tert-butyl)diphenylsilane(1358517-02-8)
• EPA Substance Registry System: (1S,4R)-3-diphenylphosphino-4-diphenylphosphoryl-cyclohex-2-enyloxy(tert-butyl)diphenylsilane(1358517-02-8)

Safety Data

• Hazardous Substances Data: 1358517-02-8(Hazardous Substances Data)

Upstream product

• 174953-42-5 (3aS,7aS)-7-bromo-2,2-dimethyl-3a,4,5,7a-tetrahydro-benzo[1,3]dioxole 
• 174817-06-2 cis-(1S,2S)-1,2-dihydroxy-3-bromocyclohex-3-ene 
• 67451-62-1 cis-(1S,2S)-1,2-dihydroxy-3-bromocyclohexa-3,5-diene 
• 108-86-1 bromobenzene 

Relevant articles and documents

Chemoenzymatic synthesis of a mixed phosphine-phosphine oxide catalyst and its application to asymmetric allylation of aldehydes and hydrogenation of alkenes

The chemoenzymatic synthesis of a Lewis basic phosphine-phosphine oxide organocatalyst from a cis-dihydrodiol metabolite of bromobenzene proceeds via a palladium-catalysed carbon-phosphorus bond coupling and a novel room temperature Arbuzov [2,3]-sigmatropic rearrangement of an allylic diphenylphosphinite. Allylation of aromatic aldehydes were catalysed by the Lewis basic organocatalyst giving homoallylic alcohols in up to 57% ee. This compound also functioned as a ligand for rhodium-catalysed asymmetric hydrogenation of acetamidoacrylate giving reduction products with ee values of up to 84%.