13600-48-1 Usage
Description
2-Chloro-6-methyl-4-(trifluoromethyl)nicotinonitrile is an organic compound characterized by its unique molecular structure, which features a chloro group, a methyl group, and a trifluoromethyl group attached to a nicotinonitrile backbone. 2-chloro-6-methyl-4-(trifluoromethyl)nicotinonitrile is known for its potential applications in various fields due to its chemical properties.
Uses
Used in Pharmaceutical Industry:
2-Chloro-6-methyl-4-(trifluoromethyl)nicotinonitrile is used as a key intermediate in the synthesis of heterocyclic derivatives, which are important for the development of novel pharmaceutical compounds. Specifically, it plays a crucial role in the preparation of DNA polymerase theta inhibitors.
These inhibitors are of significant interest in the field of cancer research and treatment, as they can potentially disrupt the DNA replication process in cancer cells, thereby inhibiting their growth and proliferation. By targeting DNA polymerase theta, a specialized enzyme involved in DNA repair and translesion synthesis, these heterocyclic derivatives may offer a new avenue for cancer therapy.
Check Digit Verification of cas no
The CAS Registry Mumber 13600-48-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,6,0 and 0 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 13600-48:
(7*1)+(6*3)+(5*6)+(4*0)+(3*0)+(2*4)+(1*8)=71
71 % 10 = 1
So 13600-48-1 is a valid CAS Registry Number.
13600-48-1Relevant articles and documents
HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER
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Page/Page column 64, (2021/02/19)
The application relates to heterocyclic amide derivatives and their use in the treatment and prophylaxis of cancer, and to compositions containing said derivatives and processes for their preparation. (Formula (I))
PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO
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Page/Page column 49; 50; 55, (2014/09/03)
This document discloses pesticidal compositions comprising molecules having the following formula ("Formula One"), - Structure- wherein the compositions further comprise one or more of additional pesticidally active components. Also disclosed are processe
PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO
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Page/Page column 50; 55; 56, (2013/07/25)
This document discloses pesticidal compositions comprising molecules having the following formula ("Formula One"): and processes related thereto.
